Old English
Sheepdogs
of Fair Oaks
We do need to speak to all families interested in adopting a puppy.
We want to make sure that all of your questions are answered, and
that families understand what adopting an OES entails. Please call us
at 573-
259-9513 or for initial contact you can e-mail us at
nancyhotz@yahoo.com
Please read our sample health guarantee below.
We will NEVER force you to give your dog any
supplements or other products in order to keep
your health guarantee in force.
I, Nancy Hotz, guarantee puppy born ____________ to Reginald and Roxanne of Fair Oaks, to be free from
any genetic or preexisting condition for three years from date of birth. If puppy is diagnosed with a terminal
genetic or preexisting condition, owner will supply Nancy Hotz with a letter from treating veterinarian, and
Nancy Hotz will refund full purchase price of $_________. If condition is not terminal, owner will return dog
for full refund. If owner wishes to keep the dog, owner will supply Nancy Hotz with veterinarian letter stating
condition and prognosis, and Nancy Hotz will refund half of the purchase price. Nancy Hotz is not
responsible for ANY veterinarian bills or other costs beyond those mentioned above.




Owner




Seller (Nancy Hotz)



DNA FOR TODAY AND TOMORROW

BY JAMES W. EDWARDS, Ph.D.

DNA certification allows owners to uniquely identify their dogs, ending all questions about identity and
parentage. Each dog tested is assigned a "DNA profile number" specific to that AKC-registered dog.
Correlating directly to that number is a genetic constitution (called a genotype) that provides absolute identity
of the dog using 10 pairs of genes.

These 10 gene pairs, which have nothing to do with conformation or health, can be used to verify the
parentage of a litter. All that is required is the genotype of the sire, dam and pup. Using capital letters to
represent genes and identifying the pairs from left to right, we can examine three Bloodhounds: the sire, the
dam and one pup (see the diagram, over)

At every gene Pair (called a locus; the plural is loci and is pronounced "lo-sigh"), the pup, Anastasia,
received one member of each pair of genes from the sire, Bruno, and the other member front the dam,
Contessa. Note that each genotype is unique. Parentage can be easily verified for Anastasia, since,
mathematically speaking, no other purebred Bloodhound has her genotype, and no other combination of sire
and dam could have produced a pup with her unique genotype.

In the AKC's DNA Certification Program, owners get a "Certificate of DNA Analysis" for their records (see
image above). Listed on each certificate is the dog's unique genotype, representing the 10 pairs of genes.
When a breeder has genotypes on file for the sire and dam of a litter, the resulting puppy genotypes are
unique and consistent only with that sire and dam. That is why DNA certification guarantees parentage, and
that is why there is great interest in the program.

By certifying only the sire and the dam, breeders can realistically eliminate all concerns about parentage: All
the new puppy owner has to do is to obtain the genotype for the pup, and it will show that the genotype of the
pup was uniquely determined at conception by combining 10 genes from the sire and 10 from the dam.
(Scientific purists require that we say one member of each of the 10 pairs is from the sire and the other from
the dam.)

Examine the "Certificate of DNA Analysis" for the DNA profile number and the genotype. The profile number
will appear on all future registration documents and is uniquely tied to the dog's genotype. After Oct. 1, 1998,
the AKC Board of Directors made DNA certification required for males whose semen is collected for
shipment or storage (i.e., frozen semen to be stored or fresh-chilled to be shipped). The purpose of this
decision, of course, is to guarantee parentage when the male is physically separated from the breeding
process. The reception to the announcement of this requirement has been overwhelmingly positive. And
Just for the record, a DNA profile is good forever - at a cost of only $40.

The AKC is continually investigating the possibilities and the realities of using DNA to guarantee the integrity
of the StudBook. In place today is the largest kennel-inspection program in the history of dogs; more than
16,000 DNA samples will have been collected and analyzed by the end of 1998.

When registration papers fail the DNA parentage verification tests at inspected kennels, litters are canceled
and AKC privileges are withdrawn.

In addition, the Parent Breed Club Program is in the process of collecting DNA samples, on a voluntary
basis, at 35 national specialties in 1998. Furthermore, the Parent Breed Club Program has been invited by
56 additional breed clubs to collect samples in 1999 and 2000.

On an individual basis, every owner and breeder can now elect to help support the AKC in its mission to
guarantee the integrity of the registry. "DNA Registered" is taking on a new meaning, and the opportunities to
focus on breeding better dogs have never been greater.

James Edwards is the AKC's director of DNA Operations and Educational Services Hee wrote "The AA BB
CC's of DNA " in the June 1998 issue of the AKC GAZE, ETTE.

Article reprinted from December 1998 AKC GAZETTE.